Endocrine Disorders: Evaluation and Management

  • Author: Todd T. Brown, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 11/14/16 (What's New)

Summary

  • Measurement of serum cortisol may produce false-negative results in some patients with HIV or chronic hepatitis due to high levels of plasma binding proteins
  • Conversely, serum cortisol level may underestimate free cortisol in patients with low plasma protein concentrations (eg, due to nephrotic syndrome or malnutrition) with potential for false-positive results

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