Endocrine Disorders: Evaluation and Management

  • Author: Todd T. Brown, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 11/14/16 (What's New)


  • In primary adrenal insufficiency, hydrocortisone (20-30 mg/day in 2 divided doses), prednisone (5 mg/day), or dexamethasone (0.5-0.75 mg/day) are given as glucocorticoid replacement, although lower doses have been advocated[Quinkler 2012]
  • Fludrocortisone (0.1-0.2 mg/day) is also given as mineralocorticoid replacement
  • [drug: Dehydroepiandrosterone] can also be considered, especially in women

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