inPractice® - Clinical Presentation and Diagnosis of Hypogonadism

Symptoms of hypogonadism are varied and nonspecific (Table 3)
Screening for hypogonadism should be considered in HIV-infected men with weight loss, sellar mass, use of medications that affect testosterone production or metabolism (glucocorticoids, ketoconazole, or opioids), end-stage renal disease and maintenance hemodialysis, moderate or severe chronic obstructive pulmonary disease, infertility, osteoporosis or low trauma fracture, and type 2 diabetes mellitus (Management Guidelines)^{[Testosterone Guidelines]}

Measuring Testosterone Levels for Hypogonadism

In patients with a normal sleep/wake cycle, laboratory assessment of hypogonadism should take place between 8:00 and 10:00 am (Management Guidelines)^{[Testosterone Guidelines]}