Management of Neurologic Diseases

  • Authors: David M. Simpson, MD; Jessica Robinson-Papp, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/1/16 (What's New)


  • Corticosteroids are often used to reduce mass effect and edema in brain lesions
  • They can also significantly reduce the size of PCNSL lesions and alter the pathologic appearance of PCNSL, with potential to confuse interpretation of treatment effects[Ferreri 2011; Morgello 2006]
  • Corticosteroids should be used judiciously and primarily in cases where edema and mass effect are of significant concern

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