inPractice® - Treatment

Management of Neurologic Diseases

Authors: David M. Simpson, MD; Jessica Robinson-Papp, MD (More Info)
Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
Last Reviewed: 4/1/16 (What's New)

Summary

Treatment guidelines suggest that the combination of ganciclovir and foscarnet may be more effective than ganciclovir alone (Management Guidelines)^{[DHHS OI]} (Management Guidelines)^{[Tunkel 2008]}
Following 3 weeks of intravenous therapy, secondary prophylaxis at half the initial dose of each antiviral agent should be provided until the CD4+ cell count is > 200 cells/mm³ for at least a few months^{[Tunkel 2008; Anduze-Faris 2000]}

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Keywords: Cryptococcus, Cytomegalovirus (CMV), IRIS, Neurologic Complications, Ophthalmologic Complications, Sexually Transmitted Diseases, Tuberculosis