Management of Neurologic Diseases

  • Authors: David M. Simpson, MD; Jessica Robinson-Papp, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/1/16 (What's New)


  • HIV-associated vacuolar myelopathy may present at any time in the course of HIV disease but may be more common in advanced disease[Dal Pan 1994]
    • Characterized by insidious onset of symmetric weakness in the lower extremities with prominent spasticity; bowel, bladder, and erectile dysfunction; and relative sparing of sensation[Di Rocco 1998a]
    • Upper extremities are usually normal
  • Diagnosis

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