Management of Neurologic Diseases

  • Authors: David M. Simpson, MD; Jessica Robinson-Papp, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/1/16 (What's New)


  • The prognosis and best course of treatment for HIV-associated myopathy are not well established
  • Immunomodulatory therapy with corticosteroids or immune globulin intravenous is usually the first line of treatment
  • Other immunosuppressive therapies used to treat polymyositis, such as methotrexate and azathioprine, may be considered, but there is little evidence of efficacy, and toxicity is a concern[Johnson 2003]

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