inPractice® - Prevalence

The prevalence of HAD, seen in up to two thirds of patients in the pre-ART era,^{[Navia 1986]} has declined substantially after the introduction of ART^{[Sacktor 2001; Sacktor 2002]}
The prevalence of neurocognitive disorders among patients with CD4+ cell counts > 500 cells/mm³ is < 5% in some community settings^{[Handelsman 1992; Krikorian 1990; Maj 1994; McKegney 1990; Wilkie 1990]}
Predictors for HAND include increased age and length of survival with HIV-1 diagnosis, low nadir CD4+ cell counts, and high baseline HIV-1 RNA^{[McCombe 2013]}