Management of Psychiatric Disorders in Patients With HIV

  • Author: Glenn J. Treisman, MD, PhD (More Info)
  • Editors in Chief: Joseph J. Eron, Jr., MD; Daniel R. Kuritzkes, MD
  • Last Reviewed: 11/5/21 (What's New)

Summary

  • Risks include higher HIV-1 RNA, lower educational level, older age, anemia, illicit drug use, metabolic syndrome, HBV or HCV coinfection, and female sex
    • Before widespread use of ART, severity of neurologic deficit directly correlated with a high cerebral spinal fluid–to–serum ratio of HIV-1 RNA[McArthur 1997]
    • In the post-ART era, mild neurocognitive disorder and depression are more accurate predictors of the severity of HAD[Stern 2001; Dunlop 2002]

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