Management of Renal Disease
Summary
- Interstitial nephritis can be acute or chronic, and acute tubular injury is more severe leading to lethal or sublethal injury of tubular cells and the loss of kidney function
- In acute tubular injury, kidney function changes rapidly from day to day throughout its nadir and recovery, causing dosing challenges for medications excreted via the kidney
- Therapeutics largely focus on maintaining proper hemodynamics and withdrawing any nephrotoxic medications
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