Management of Renal Disease

  • Author: Mohamed G. Atta, MD, MPH (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 3/14/17 (What's New)


  • Interstitial nephritis can be acute or chronic, and acute tubular injury is more severe leading to lethal or sublethal injury of tubular cells and the loss of kidney function
  • In acute tubular injury, kidney function changes rapidly from day to day throughout its nadir and recovery, causing dosing challenges for medications excreted via the kidney
  • Therapeutics largely focus on maintaining proper hemodynamics and withdrawing any nephrotoxic medications

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