Management of Renal Disease

  • Author: Mohamed G. Atta, MD, MPH (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 3/14/17 (What's New)


  • Serum chemistry panel, complete urinalysis, albuminuria quantitation, assessment of temporal trends in estimated GFR (blood pressure, blood glucose control in diabetic patients), evaluation of markers of proximal tubular dysfunction (especially in patients receiving tenofovir DF), and renal sonogram make up the recommended evaluation for new kidney disease in patients with HIV infection (Management Guidelines)[Lucas 2014]
  • All medications should be reviewed for potential nephrotoxicity, with modification as needed[Lucas 2014]
  • Consult a nephrologist when there is a significant decline in GFR that fails to resolve with removal of nephrotoxic drugs, albuminuria (> 300 mg/day), hematuria combined with either albuminuria or proteinuria, or increased blood pressure[Lucas 2014]
  • Acute Renal Disease
      Tubular Damage
        Glomerular Damage
          Role of Biopsy in Assessing Acute Kidney Disease
          Chronic Renal Failure
            Role of Biopsy in Assessing Chronic Kidney Disease

          Action required