Management of IRIS

  • Authors: Irini Sereti, MD, MHS; Philip Grant, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/1/16 (What's New)


  • INSHI has established diagnostic criteria for unmasking and paradoxical TB IRIS (Table 3)[Meintjes 2008]
  • TB IRIS generally occurs within the first 60 days of ART[Breton 2004; Shelburne 2005]
  • Paradoxical TB IRIS is characterized by recurrent constitutional symptoms and worsening respiratory symptoms and parenchymal lesions

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Keywords: IRIS