Management of IRIS

  • Authors: Irini Sereti, MD, MHS; Philip Grant, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/1/16 (What's New)


  • MAC IRIS most commonly presents as fever and focal lymphadenitis, usually within the first 2 months of ART[Race 1998; Shelburne 2002; Shelburne 2005; Phillips 2005; Murray 2001]
  • Biopsies of involved tissues generally show few acid-fast bacilli with many well-formed granulomas, and bone marrow and blood cultures are usually negative

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