inPractice® - Tipranavir

Special Considerations and Clinical Management of HIV-Infected Drug Users

Author: Frederick L. Altice, MD (More Info)
Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
Last Reviewed: 4/1/16 (What's New)

Summary

Standard dosing of tipranavir/ritonavir 500/200 mg twice daily may result in a decrease in methadone levels requiring an increase in methadone dose^{[FDA Tipranavir]}
Buprenorphine levels are not significantly decreased with tipranavir/ritonavir 500/200 mg twice daily^{[Bruce 2009a]}

Action required

Login now to access all of your entitled content
or
View additional options to gain access to this content

Keywords: Drug-Drug Interactions, Initial Antiretroviral Therapy, IV Drug Use, Pharmacokinetics, Special Populations