Special Considerations and Clinical Management of HIV in Patients With Substance Use Disorder
Summary
- Buprenorphine levels are significantly increased with either atazanavir 400 mg daily or atazanavir/ritonavir 300/100 mg daily[McCance-Katz 2007]
- Patients should be monitored for this effect when these drugs are given together and buprenorphine dose adjustment considered[FDA Atazanavir]
- Atazanavir should not be given unboosted with buprenorphine[FDA Atazanavir]
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