Special Considerations Related to Aging in HIV-Infected Patients
Summary
- Clinical Response to Therapy
- Combination ART provides substantial benefit to older patients[Bhaskaran 2008b; Porter 2003; Ewings 2008; Davis 2013]
- Risk of AIDS or death after ART initiation remains greater in older vs younger patients, after adjusting for CD4+ cell count, HIV-1 RNA, disease stage, and previous injection drug use (Figure 3)[COHERE 2008; Ewings 2008; May 2007; Mussini 2008; Greenbaum 2008]
- Inferior clinical outcomes in older HIV-infected persons are not explained by poor virologic response to ART
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Keywords: HIV and Older Patients