Agents Used in Antiretroviral Therapy

  • Authors: Philip Grant, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 7/19/21 (What's New)

Summary

  • NRTIs form the backbone of most antiretroviral regimens
  • There are 8 NRTIs currently in clinical use (Table 3) and 5 that are still commonly used
  • There are more than 10 coformulations involving NRTIs in clinical use or in advanced clinical development (Table 4)
    • Abacavir
      Emtricitabine
        Lamivudine
          Tenofovir DF
            Tenofovir AF

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            Keywords: Cardiovascular Disease, Hematologic Complications, Initial Antiretroviral Therapy, Mitochondrial Disorders, Neurologic Complications, Special Populations, Treatment Complications, Viral Hepatitis Coinfection

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