Management of IRIS

  • Authors: Irini Sereti, MD, MHS; Philip Grant, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/1/16 (What's New)


  • CMV IRIS most commonly presents with ocular disease, although pneumonitis, acute appendicitis, and sialadenitis have also been reported[Miller 2000; Faldetta 2014; Sheikh 2013]
  • A more inflammatory reaction known as immune recovery vitritis can occur later in the course of ART
  • Patients who develop immune recovery vitritis require long-term ophthalmologic follow-up

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