Viral Infections

  • Author: Jin S. Suh, MD, FACP; Humberto R. Jimenez, PharmD, BCPS, AAHIVP (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 8/1/21 (What's New)


  • Choice of initial therapy should be individualized to each patient, taking into account tolerance of medications, earlier exposure to any anti-CMV drugs, location and severity of lesions, and clinical judgment (Table 4 and Table 5) (Management Guidelines)[CDC OI]
  • Recommended treatment options for CMV retinitis include IV ganciclovir and oral valganciclovir, or IV ganciclovir with the option of weekly intravitreal injections of ganciclovir or foscarnet and followed by oral valganciclovir maintenance therapy
    • Intravitreal injections of ganciclovir or foscarnet in addition to systemic therapy are recommended for patients with sight-threatening lesions

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