Overview of HIV Prevention

  • Author: Sharon L. Hillier, PhD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 9/4/20 (What's New)


  • Antiretroviral PrEP for HIV infection can be delivered orally or topically as a gel, film, suppository, or sustained-release intravaginal ring[Baeten 2008]
  • WHO recommends offering oral tenofovir DF–containing PrEP to individuals at substantial risk of acquiring HIV as an additional prevention option in combination with other preventive strategies (Management Guidelines)[WHO 2016]
  • CDC provides guidelines on the use of PrEP in MSM (Table 3), in heterosexually active adults (Table 4), and in people who inject drugs (Table 5) (Management Guidelines)[CDC PrEP]
  • Oral Pre-Exposure Prophylaxis
      Topical Pre-Exposure Prophylaxis
        Other New Strategies for Pre-Exposure Prophylaxis

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