Agents Used in Antiretroviral Therapy

  • Authors: Philip Grant, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 10/1/18 (What's New)

Summary

  • NNRTIs bind to and stereotypically inhibit HIV reverse transcriptase outside of active domain
  • Currently, there are 6 FDA-approved NNRTIs (Table 9)
  • Rash is a classwide adverse effect with use of currently approved NNRTIs
  • Efavirenz
      Etravirine
        Rilpivirine
          Doravirine

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