Modifying Antiretroviral Therapy in Virologically Suppressed HIV-Infected Patients
Summary
- Virologically suppressed patients with a high risk of cardiovascular disease and nephrotoxicity may need to switch to a new regimen that excludes or limits both ritonavir and NRTIs Switching to a Boosted PI Plus Lamivudine
- The use of dual atazanavir/ritonavir plus lamivudine therapy for maintenance of viral suppression has been evaluated in several trials
- SALT: dual boosted atazanavir plus lamivudine was noninferior to triple therapy of boosted atazanavir plus 2 NRTIs for maintenance of virologic suppression through 48 weeks[Perez-Molina 2015]
- SALT: dual boosted atazanavir plus lamivudine was noninferior to triple therapy of boosted atazanavir plus 2 NRTIs for maintenance of virologic suppression through 48 weeks[Perez-Molina 2015]
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Keywords: Dyslipidemia, Fat Perturbations, Switch Strategies