Agents Used in Antiretroviral Therapy

  • Authors: Philip Grant, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 9/10/19 (What's New)

Summary

  • Darunavir in combination with other antiretroviral agents is indicated for treatment of HIV infection; it must be coadministered with ritonavir or cobicistat as a boosted PI[FDA Darunavir]
  • Darunavir is active against many PI-resistant HIV variants
  • Darunavir is given orally at a dose of 600 mg with ritonavir 100 mg twice daily for treatment-experienced with darunavir-associated resistance or 800 mg with ritonavir 100 mg once daily for all other patients

    Action required

    Keywords: Cardiovascular Disease, Initial Antiretroviral Therapy, Special Populations, Treatment Complications

    ©2018 Clinical Care Options, LLC. All Rights Reserved.

    The materials published via inPractice® reflect the views of the reviewers or authors of the material, not those of Clinical Care Options, LLC, the accredited provider, or the companies providing educational grants. The materials may discuss uses and dosages for therapeutic products that have not been approved by the United States Food and Drug Administration. A qualified healthcare professional should be consulted before using any therapeutic product discussed. Readers should verify all information and data before treating patients or using any therapies described in these materials.