Non–AIDS-Defining Cancers

  • Authors: David Aboulafia, MD (More Info)
  • Editors in Chief: Joseph J. Eron, Jr., MD; Daniel R. Kuritzkes, MD
  • Last Reviewed: 11/15/21 (What's New)


  • Squamous cell carcinoma comprises majority of primary anal cancers with many patients presenting in advanced stages
    • Anal intraepithelial neoplasia (AIN) divided into 3 grades based on level of dysplasia (Figure 3)
  • Screening strategies under investigation include high-resolution anoscopy, anal cytology (anal Pap test), and anal human papillomavirus detection

Action required