Viral Infections

  • Author: Jin S. Suh, MD, FACP (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 7/26/16 (What's New)


  • Several studies have shown that treatment of HSV-2 in coinfected patients may reduce their HIV-1 RNA modestly or reduce the risk of clinical progression, excluding patients on ART
  • Some have suggested that in resource-limited environments, use of acyclovir may be an option for people with HIV who are not eligible for ART because they have not yet reached the threshold for ART initiation applicable in their particular country
    • However, because anti-HSV therapies do not prevent HIV transmission, they should not be used to delay HIV progression in the place of ART when ART is available[Celum 2010; CDC OI]

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