inPractice® - Clinical Manifestations and Complications of HIV in Older Patients

HAD and, to a lesser degree, HIV-associated esophageal candidiasis and wasting are more frequent in older vs younger individuals^{[CDC 1998; Balslev 1997; Valcour 2004; Longo 2008]}
Older HIV-infected patients are more likely to develop comorbid conditions, eg, non-AIDS-defining malignancies, diabetes, hypertension, and liver, pulmonary, vascular, and renal disease^{[Weber 2006; Phillips 2008; Goulet 2007; Monforte 2008; Lodwick 2010; Negin 2012; Schouten 2012; Hasse 2011]}
- Many of these conditions are more common in older HIV-infected patients than in similarly aged HIV-uninfected individuals^{[Deeks 2009; Justice 2010a; Currier 2008; Grulich 2007; Brown 2006; Longenecker 2009; Nkhoma 2010; Guaraldi 2011]}