The Approach to the Patient With HIV With Specific Symptom Complexes/Common Presentations

  • Author: Steven C. Johnson, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 10/31/21 (What's New)


  • Patients may develop an acute febrile illness following acquisition of HIV, termed acute or primary HIV infection
    • Signs and symptoms include fever, maculopapular skin rash, headache, myalgias, sore throat, and lymphadenopathy
    • Laboratory findings include leukopenia, moderately elevated hepatic transaminases, and CSF pleocytosis[Kahn 1998]

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