Tuberculosis and Other Mycobacterial Infections

  • Authors: Richard E. Chaisson, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 3/30/17 (What's New)

Summary

  • WHO guidelines recommend that all children and adults infected with HIV should be screened for symptoms of TB at every clinical encounter, with further investigation for those who report symptoms (Management Guidelines)[WHO 2010 TB]
    • Patients receiving ART who do not have any of the 4 clinical symptoms of TB (current cough, fever, weight loss, and night sweats) should receive isoniazid prophylaxis
    • Patients should receive isoniazid for ≥ 6 months; extend isoniazid therapy to ≥ 36 months in settings with high HIV and TB prevalence

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