Primary Care for HIV-Infected Patients in Resource-Limited Settings

  • Authors: Charles van der Horst, MD; F. Parker Hudson, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 9/4/18 (What's New)


  • UNAIDS estimates that approximately 9.7 million people in resource-poor nations were receiving ART at the end of 2012, which represents 61% of people who qualified for treatment under the 2010 WHO treatment guidelines[UNAIDS 2013a]
  • Current WHO guidelines recommend that all persons living with HIV be offered lifelong ART regardless of clinical stage or CD4+ cell count, with priority given to those with CD4+ cell counts ≤ 350 cells/mm³ and those with advanced HIV clinical disease (Management Guidelines)[WHO ART]
  • To further scale up access to ART for treatment and prevention of HIV in resource-limited settings, the authors of this chapter recommend a public health approach that emphasizes management of HIV-infected patients across a variety of settings where advanced laboratory monitoring may not be available
  • When to Start
      Antiretroviral Regimens in the Developing World
        On-Treatment Monitoring
            When to Substitute for Toxicity
              When to Switch for Treatment Failure
                When to Stop Therapy

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