Management of Neurologic Diseases

  • Authors: David M. Simpson, MD; Jessica Robinson-Papp, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/1/16 (What's New)


  • HAND is the most common CNS complication of HIV, although severe forms are rare
    • Presents with slowly progressive cognitive decline, with or without depression, withdrawal, and psychomotor slowing
  • Parkinsonian symptoms such as decreased facial expression, mildly increased muscle tone, frontal release signs, and mild slowing of gait are common[Robinson-Papp 2008]

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