Primary Care for HIV-Infected Patients in Resource-Limited Settings
Summary
- Patients unable to tolerate adverse effects require ART modification (Table 7)
- Stavudine is associated with toxicities such as lipodystrophy, metabolic syndrome, lactic acidosis, pancreatitis, and peripheral neuropathy, and should no longer be used in first-line ART regimens[WHO ART]
- Substitution of stavudine with zidovudine or tenofovir DF should be implemented as soon as possible
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