Clinical Implications of HIV Pathogenesis
Summary
- Initiation of potent ART results in a decay in plasma HIV-1 RNA levels and an increase in CD4+ cell count[Ho 1995; Wei 1995]
- Initial phase of viral decay reflects elimination of free virus and the turnover of productively infected, activated CD4+ T cells
- A more gradual phase follows that is thought to reflect clearance of infection in cells that divide less quickly
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Keywords: Initial Antiretroviral Therapy