Management of AIDS-Defining Cancers
Summary
- PCNSL is a subtype of DLBCL strongly related to Epstein-Barr virus infection and usually occurs in patients with advanced HIV disease (CD4+ cell count < 50 cells/mm3)
- Cerebrospinal fluid cytology, toxoplasmosis serologic testing, and an empiric trial of antibiotics may be needed to distinguish differential diagnoses such as infections, other tumors, and disease entities (Management Guidelines)[BHIVA HIV Cancer]
- Bone marrow biopsy, chest and abdomen CT scan, testicular ultrasound, and physical examination to detect occult systemic lymphoma is also recommended[BHIVA HIV Cancer]
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Keywords: Cancer