Management of IRIS

  • Authors: Irini Sereti, MD, MHS; Philip Grant, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/1/16 (What's New)


  • Pathogen-specific antimicrobials should be initiated or continued in patients diagnosed with IRIS
  • Corticosteroids are usually needed in serious or refractory IRIS cases
  • Use of prednisone has been shown to reduce IRIS symptoms in patients with paradoxical TB IRIS[Meintjes 2010]

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