Timing of Initiation of First-line Antiretroviral Therapy

  • Authors: Marshall J. Glesby, MD, PhD; Timothy J. Wilkin, MD, MPH (More Info)
  • Section Editor: Joel E. Gallant, MD, MPH
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/1/16 (What's New)

Summary

  • Treatment guidelines recommend that all patients should be considered for ART initiation, although certain groups should be prioritized (Table 4)
    • These patients may have higher risk of morbidity and mortality from uncontrolled HIV infection or be at greater risk for transmitting HIV
    • Major antiretroviral treatment guidelines differ in recommendations for such patients
    • Children and Infants
      Coronary Heart Disease
        Hepatitis Virus Coinfection
          HIV-Associated Nephropathy
            Malignancies
              Pregnancy and Breastfeeding
                HIV Transmission in Serodiscordant Relationships and the Community: Test and Treat

                Action required

                Keywords: Cardiovascular Disease, Initial Antiretroviral Therapy, Pregnancy, Renal Complications, Special Populations, Viral Hepatitis Coinfection

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