inPractice® - Treatment of Latent Tuberculosis Infection

Tuberculosis and Other Mycobacterial Infections

Authors: Richard E. Chaisson, MD (More Info)
Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
Last Reviewed: 3/30/17 (What's New)

Summary

Patients with HIV infection and LTBI should be treated with a prophylactic regimen to prevent progression to active TB disease (Table 6, Table 7)^{[DHHS Adult OI; MMWR 2000; Gordin 2000; MMWR 2011; Martinson 2011]}
- Nine months of isoniazid is a preferred first-line prophylactic regimen in the United States^{[DHHS Adult OI]}
  - A 6-month course of isoniazid may be more cost-effective in developing countries^{[MMWR 2000]}

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Keywords: Renal Complications, Tuberculosis