The Approach to the Patient With HIV With Specific Symptom Complexes/Common Presentations

  • Author: Steven C. Johnson, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 10/31/21 (What's New)


  • Comorbidities often encountered in HIV infection include HBV, HCV, HPV-related diseases, TB, STDs, polysubstance abuse, and mental illness
  • Comorbidities that are prevalent in the general population may have increased incidence in patients with HIV, such as non-AIDS–defining malignancies, myocardial infarction, end-stage renal disease[Patel 2008; Althoff 2013]
  • In settings where ART is widely available, most deaths occurring in patients with HIV are not related to AIDS, but to non-AIDS conditions such as viral hepatitis, cancers, and cardiovascular disease[Lewden 2005; Smith 2014]

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