Agents Used in Antiretroviral Therapy

  • Authors: Philip Grant, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 7/19/21 (What's New)

Summary

  • Rilpivirine therapy failure is associated with mutations at L100I, K101E/P, E138A/G/K/Q/R, V179L, Y181C/I/V, Y188L, H221Y, F227C, and M230I/L[Wensing 2017]
  • Rilpivirine is indicated in combination with other antiretroviral agents for treatment of HIV infection in treatment-naive adult patients with HIV-1 RNA ≤ 100,000 copies/mL in United States[FDA Rilpivirine]

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