Agents Used in Antiretroviral Therapy

  • Authors: Philip Grant, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 7/19/21 (What's New)


  • Entry inhibitors block binding of gp120 to CD4 receptors
  • Currently only 1 FDA-approved CCR5 antagonist is available: maraviroc (Table 11)
  • Ibalizumab-uiyk prevents the interaction of gp 120 with CCR5 and CXCR4 and is approved for use in heavily treatment–experienced patients with multidrug-resistant HIV
  • Ibalizumab

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