Hepatic Disease in Patients With HIV

  • Author: Mark S. Sulkowski, MD (More Info)
  • Editors in Chief: Joseph J. Eron, Jr., MD; Daniel R. Kuritzkes, MD
  • Last Reviewed: 11/13/21 (What's New)


  • HIV infection can accelerate progression of HBV-related liver disease
  • US guidelines recommend initiating ART that includes 2 agents active against HBV in all patients coinfected with HIV and HBV (Management Guidelines)[DHHS ART]
  • Patients Refusing or Unable to Tolerate HIV Therapy or Who Are HIV Long-term Nonprogressors
      Patients Who Cannot Receive Tenofovir Disoproxil Fumarate or Tenofovir Alafenamide
        Patients Who Have Drug-Resistant HBV

        Action required