Agents Used in Antiretroviral Therapy

  • Authors: Philip Grant, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 10/1/18 (What's New)

Summary

  • Tenofovir AF in combination with other antiretroviral agents is indicated for treatment of HIV infection[FDA COBI/EVG/FTC/TAF]
  • Tenofovir AF has superior antiviral efficacy through 144 weeks and reduced bone and kidney toxicity when compared with tenofovir DF[Arribas 2017]
  • Tenofovir AF available as a single agent agent (approved for treatment of HBV) and as part of several coformulations:

    Action required

    Keywords: Cardiovascular Disease, Hematologic Complications, Initial Antiretroviral Therapy, Mitochondrial Disorders, Neurologic Complications, Special Populations, Treatment Complications, Viral Hepatitis Coinfection

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