Key Principles and Recommended Regimens for First-line Antiretroviral Therapy

  • Author: Paul E. Sax, MD (More Info)
  • Editors in Chief: Joseph J. Eron, Jr., MD; Daniel R. Kuritzkes, MD
  • Last Reviewed: 11/12/21 (What's New)


  • Choice of initial antiretroviral therapy should be tailored to patient characteristics and preferences, taking into account virus factors, patients factors, and drug factors (Table 8)
    • Virus factors: viral load, transmitted resistance, tropism
    • Patient factors: preferences concerning dosing, pregnancy, comorbidity, vocational

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