Agents Used in Antiretroviral Therapy
Summary
- Maraviroc, in combination with other antiretroviral agents, is indicated for adult patients infected with CCR5-tropic HIV only[FDA Maraviroc]
- Maraviroc is a substrate for cytochrome P450 3A4 and dosed according to other agents in regimen (Table 18)[FDA Maraviroc]
- In clinical trials, maraviroc-containing regimens have been associated with greater CD4+ cell count increases than comparator regimens, but clinical implications of this finding have not been elucidated
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