Laboratory Assays in the Clinical Management of Antiretroviral Therapy
Summary
- The AIDS Clinical Trials Group and the DHHS guidelines define virologic failure as confirmed viral load > 200 copies/mL while receiving antiretroviral therapy
- Any rebound in viral load from undetectable level should be confirmed with repeat testing
- Persistent low-level viremia, even at levels < 200 copies/mL, may lead to selection of resistance mutations[Li 2012; Taiwo 2011]
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