inPractice® - Antiretroviral Therapy Beyond Infancy in Children With HIV

Management of Children With or Exposed to HIV

Authors: James A. McAuley, MD, MPH; Mariam Aziz, MD (More Info)
Associate Editor: Judith S. Currier, MD, MSc
Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
Last Reviewed: 7/12/18 (What's New)

Summary

Decisions about ART initiation in children who present with HIV infection beyond infancy are similar to those in adults, although treatment options are more limited
Resistance testing should be performed before ART initiation

When to Start Antiretroviral Therapy in Children 1 Year of Age or Older

DHHS guidelines recommend ART initiation in all children with HIV regardless of clinical stage, CD4+ cell count, or HIV-1 RNA level (Table 3) (Management Guidelines)^{[DHHS Pediatric]}

Choice of Initial Antiretroviral Therapy in Children Older Than 1 Year of Age

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Keywords: Initial Antiretroviral Therapy, Pediatric/Adolescent Patients, Pediatric/Adolescent Patients