Bacterial Infections

  • Author: Harjot K. Singh, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 4/1/16 (What's New)

Summary

  • Patients with C difficile infection should discontinue use of implicated agents when possible and avoid antiperistaltic agents and narcotics (Management Guidelines)[Leffler 2009]
  • The Society for Healthcare Epidemiology of America/Infectious Diseases Society of America guidelines recommend oral metronidazole as the preferred treatment and oral vancomycin as an alternative agent or for more severe disease (Management Guidelines)[Cohen 2010]
  • Recommended treatment for relapse is to repeat standard treatment, sometimes followed by a taper with 125 mg orally every other day for ≥ 6 weeks

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