Overview of HIV Prevention
Summary
- A series of HIV vaccine trials testing recombinant vaccine candidates has been unsuccessful[Flynn 2005; Pitisuttithum 2006; Buchbinder 2008]
- RV144, a candidate vaccine using a prime-boost vaccine strategy, demonstrated modest efficacy in a randomized trial[Rerks-Ngarm 2009]
- VRC01 vaccine slightly delayed viral round in virologically suppressed patients discontinuing ART, but viral suppression was not maintained at 8 weeks in 2 phase I trials[Bar 2016]
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Keywords: Biomedical Prevention