Management of Renal Disease
Summary
- Boosted PIs and tenofovir DF have been associated with significant declines in renal function in combination and individually[Goicoechea 2008; Gallant 2009; Morlat 2013]
- Tenofovir DF should be avoided in patients with eGFR < 60 mL/min/1.73 m2[Lucas 2014]
- Tenofovir AF is less nephrotoxic than tenofovir DF in clinical trials and is recommended as either preferred over or as an appropriate alternative to tenofovir DF in US guidelines
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Keywords: Renal Complications, Treatment Complications