Clinical Implications of HIV Pathogenesis

  • Author: David M. Margolis, MD (More Info)
  • Editors in Chief: Daniel R. Kuritzkes, MD; Joseph J. Eron, Jr., MD
  • Last Reviewed: 9/4/18 (What's New)


  • Viral replication and an inflammatory host response induce destruction of CD4+ cells early in acute HIV infection
  • Activation of CD4+ cells increases dramatically during acute HIV infection[Deeks 2004; Douek 2009]
    • Clinical Outcomes of Treating Early HIV Infection

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