Special Considerations Related to Aging in Persons With HIV
Summary
- Older patients who achieve and sustain virologic suppression after ART initiation have less robust CD4+ cell count recovery compared with younger people[Engsig 2014; Goetz 2001; Kaufmann 2005; Florence 2003; Baker 2008; Zhang 2020]
- Further impairment of the immunologic response occurs in patients who do not achieve virologic suppression[COHERE 2008; Silverberg 2007; Florence 2003; Kaufmann 2003; Khanna 2008; Gandhi 2006]
- In the general population of older persons, slow CD4+ cell recovery reflects age-related decreases of thymic naive CD4+ cell production[Haynes 2000; Robbins 2009]
Action required
- Login now to access all of your entitled content
or - View additional options to gain access to this content
Keywords: HIV and Older Patients